UPS operates one of the world's largest airlines using more than 600 aircraft to serve more than 200 countries and territories worldwide. The company's extensive air network includes international air hubs in Cologne, Taipei, Miami (to serve Latin America), an intra-Asia hub in the Philippines and, the UPS Worldport in Louisville, Kentucky (the four million square foot heart of UPS's global air network).

In addition to its airline, UPS is also a pioneer in developing aviation technologies to enhance the safety and efficiency of the aviation industry.